100% certain the factory spare will not have TPMS. We, or USDM 2016 at least, also has no access to anything TPMS related in our SYNC3 menus.
Some people replace the factory spare with the best tire from the previous set on a full size wheel. This used to be a common practice for me but IIRC don't think the Fiesta has a well large enough a the full size spare. As someone already mentioned, the relearn procedure only accommodates four sensors, not five. (you'd have to forget/neglect to do the relearn following a tire/wheel swap)
On the maintaining a spare tire, hose down the sidewalls in silicon spray then garbage bag your spare. Not being exposed to new air in the bag, it won't oxidize like it did before. Fifteen years in the trunk and it'll come out seeming like new, come time to actually use it. Prudent to occasionally test your air pump; as well as top-off your spare. That last part minimizes time spent as a vulnerable target on the side of the road.
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